Extraction socket grafting using recombinant human bone morphogenetic protein-2-clinical implications and histological observations

Abstract Objectives Rehabilitation of edentulous ridges to promote the insertion dental implants has been key indicator for retaining osseous structures since tooth extraction. Recombinant Bone Morphogenetic Protein-2(rhBMP-2) is exploited bone augmentation due its osteoinductive capacity. The objective study determine effectiveness induction implant placement by rhBMP-2 delivered on beta-tricalcium phosphate graft (?-TCP) and PRF following Results Minimal changes in width crestal relative baseline values were found three months after socket grafting. A loss mesiodistal buccolingual aspects 0.6 ± 0.13 mm 0.5 was found, respectively. While drilling before placement, bone's clinical hardness evaluated through tactile analogous into spruce or white pine wood. Total radiographic filling seen 3 no additional needed during placement. Besides, histology shows residual particles. Therefore, data from this demonstrated that novel combination + ?-TCP mixed with an effect de novo formation can be recommended grafting